DRUG NAME

Pletal ( Cilostazol/Pletal )

WARNINGS/PRECAUTIONS

Do not use Pletal if:

• you have heart failure.
• you are allergic to any ingredient in Pletal;

Contact your doctor or health care provider right away if any of these apply to you.

Important:

Pletal may cause dizziness. This effect may be worse if you take it with alcohol or certain medicines. Use Pletal with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.

Tell your doctor or dentist that you take Pletal before you receive any medical or dental care, emergency care, or surgery. Lab tests, including complete blood cell counts, may be performed while you use Pletal. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.

Pregnancy and breast-feeding: If you are pregnant or become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Pletal while you are pregnant. It is not known if Pletal is found in breast milk. Do not breast-feed while taking Pletal.

MISSED DOSE

If you miss a dose of Pletal take it as soon as possible. If several hours have passed or if it is nearing time for the next dose, do not double the dose to catch up, unless advised by your health care provider. Do not take 2 doses at once. If more than one dose is missed, contact your health care provider or pharmacist.

DRUG CLASS AND MECHANISM

Pletal is a phosphodiesterase type 3 inhibitor. Pletal works by widening arteries that supply blood to the legs and it also decreases the ability of platelets (particles in the blood involved in blood clotting) to stick together.

POSSIBLE SIDE EFFECTS

Check with your doctor if any of these most common side effects persist or become bothersome:

• bloating or swelling of ankles, feet, or hands;
• swelling of the legs and feet.
• sore throat;
• diarrhea;
• nausea;
• abnormal stools;
• increased cough;
• dizziness;
• muscle aches;
• feeling of a whirling motion;
• infection;
• back pain;
• gas;
• indigestion;
• stomach pain;
• headache;
• runny nose;

Seek medical attention right away if any of these severe side effects occur:

• vomiting material that looks like coffee grounds.
• unusual bruising or bleeding;
• fast or irregular heartbeat;
• black, tarry stools;
• pounding in the chest;
• severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue);

DRUG USES

Pletal reduces attacks of intermittent claudication (pain, cramping, numbness, or weakness in the foot, hip, thigh, or buttocks) that may occur after walking.

HOW TAKEN

Use Pletal as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Take Pletal by mouth at least 30 minutes before or 2 hours after eating.

Do not eat grapefruit or drink grapefruit juice while you take Pletal.

The effects of Pletal are not immediate. Although you may experience the benefits of Pletal 2 to 4 weeks after beginning treatment, treatment for up to 12 weeks may be necessary before Pletal takes effect.

MORE INFORMATION

This information is a summary only. It does not contain all information about Pletal . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

STORAGE

Store at the room temperature away from moisture and sunlight. Keep out of the reach of children.

What is the shelf life of the pills?

• The expiry date is mentioned on each blister. It is different for different batches. The shelf life is 2 years from the date of manufacture and would differ from batch to batch depending on when they were manufactured.