WHAT IS Lopressor/Metoprolol?

Metoprolol/Lopressor is in a group of drugs called beta-blockers. Beta-blockers affect the heart and circulation (blood flow through arteries and veins).

Metoprolol/Lopressor is used to treat angina (chest pain) and hypertension (high blood pressure). It is also used to treat or prevent heart attack.

Metoprolol/Lopressor may also be used for purposes other than those listed in this medication guide.

WHAT HAPPENS IF I OVERDOSE?

Seek emergency medical attention if you think you have used too much of this medicine.

Symptoms of an metoprolol/Lopressor overdose may include uneven heartbeats, shortness of breath, bluish-colored fingernails, dizziness, weakness, fainting, or seizure (convulsions).

WHAT SHOULD I AVOID WHILE TAKING Lopressor/Metoprolol?

Metoprolol/Lopressor can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert. Avoid drinking alcohol, which could increase drowsiness and dizziness while you are taking metoprolol/Lopressor .

WHAT OTHER DRUGS WILL AFFECT Lopressor/Metoprolol?

Before taking metoprolol/Lopressor , tell your doctor if you are using:

• medicine for asthma or other breathing disorders, such as albuterol/Albuterol cr ( Ventolin/Ventolin sulfate , Proventil/Proventil cr ), bitolterol (Tornalate), metaproterenol (Alupent), pirbuterol (Maxair), terbutaline ( Brethaire , Brethine , Bricanyl), and theophylline (Theo-Dur, Theolair/Theolair cr );
• anti-malaria medications such as chloroquine ( Aralen ) or hydroxychloroquine (Plaquenil, Quineprox);
• digoxin/Lanoxin (digitalis, Lanoxin );
• a diuretic (water pill) such as amiloride (Midamor, Moduretic ), chlorthalidone (Hygroton, Thalitone), furosemide ( Lasix ), hydrochlorothiazide (HCTZ, HydroDiuril , Hyzaar , Lopressor , Vasoretic, Zestoretic ), spironolactone (Aldactazide, Aldactone ), triamterene (Dyrenium, Maxzide, Dyazide), torsemide ( Demadex ), and others; or
• clonidine (Catapres);
• an MAO inhibitor such as isocarboxazid (Marplan), tranylcypromine (Parnate), phenelzine (Nardil), or selegiline/Eldepryl ( Eldepryl , Emsam);
• medicine to treat depression or mental illness, such as bupropion/Zyban sr ( Wellbutrin/Wellbutrin sr , Zyban/Zyban sr ), fluoxetine ( Prozac , Sarafem ), paroxetine ( Paxil ), thioridazine ( Mellaril ), and others;
• a diabetes medication such as insulin, glyburide (Diabeta, Micronase , Glynase), glipizide ( Glucotrol/Glucotrol xl ), chlorpropamide (Diabinese), or metformin ( Glucophage );
• ritonavir/Norvir ( Norvir );
• a heart medication such as nifedipine/Procardia ( Procardia , Adalat/Adalat cc er ), quinidine (Quinaglute, Quinidex), propafenone (Rythmol), reserpine (Serpasil), verapamil ( Calan/Calan sr , Verelan/Verelan sr , Isoptin/Isoptin sr ), diltiazem/Diltiazem cd ( Cartia/Cartia er , Cardizem );
• cold medicines, stimulant medicines, or diet pills.
• terbinafine/Lamisil ( Lamisil );

If you are using any of these drugs, you may not be able to take metoprolol/Lopressor , or you may need dosage adjustments or special tests during treatment.

There may be other drugs not listed that can affect metoprolol/Lopressor . Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

WHAT IS THE MOST IMPORTANT INFORMATION I SHOULD KNOW ABOUT Lopressor/Metoprolol?

Do not stop taking metoprolol/Lopressor without first talking to your doctor. Stopping suddenly may make your condition worse.

If you need to have any type of surgery, you may need to temporarily stop using metoprolol/Lopressor . Be sure the surgeon knows ahead of time that you are using metoprolol/Lopressor .

Metoprolol/Lopressor can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert. Avoid drinking alcohol, which could increase drowsiness and dizziness while you are taking metoprolol/Lopressor .

Metoprolol/Lopressor is only part of a complete program of treatment for hypertension that may also include diet, exercise, and weight control. Follow your diet, medication, and exercise routines very closely if you are being treated for hypertension.

Hypertension often has no symptoms, so you may not even feel that you have high blood pressure. Continue using this medicine as directed, even if you feel well. You may need to use blood pressure medication for the rest of your life.

WHAT SHOULD I DISCUSS WITH MY HEALTHCARE PROVIDER BEFORE TAKING Lopressor/Metoprolol?

Do not use this medication if you are allergic to metoprolol/Lopressor , or if you have:

• a heart problem such as heart block, sick sinus syndrome, or slow heart rate;
• pheochromocytoma; or
• problems with circulation (such as Raynaud's syndrome).

Before taking metoprolol/Lopressor , tell your doctor if you have:

• low blood pressure;
• asthma, bronchitis, emphysema;
• liver or kidney disease;
• diabetes;
• a thyroid disorder; or
• depression;
• congestive heart failure;
• myasthenia gravis.

If you have any of these conditions, you may not be able to use metoprolol/Lopressor , or you may need a dosage adjustment or special tests during treatment.

FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Metoprolol/Lopressor can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

WHAT HAPPENS IF I MISS A DOSE?

Take the missed dose as soon as you remember. If your next dose is less than 4 hours away, skip the the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.

HOW SHOULD I TAKE Lopressor/Metoprolol?

Take metoprolol/Lopressor exactly as it was prescribed for you. Do not take the medication in larger amounts or for longer than recommended by your doctor.

Take this medication with a full glass of water.

Take metoprolol/Lopressor at the same time every day.

A Toprol XL tablet can be divided in half if your doctor has told you to do so. The half tablet should be swallowed whole, without chewing or crushing. Chewing or crushing the pill could cause too much of the drug to be released at one time. Do not skip doses or stop taking metoprolol/Lopressor without first talking to your doctor. Stopping suddenly may make your condition worse.

To be sure this medication is helping your condition, your blood pressure will need to be checked on a regular basis. It is important that you not miss any scheduled visits to your doctor.

If you need to have any type of surgery, tell the surgeon that you are using metoprolol/Lopressor . You may need to briefly stop using metoprolol/Lopressor before having surgery.

Metoprolol/Lopressor is only part of a complete program of treatment for hypertension that may also include diet, exercise, and weight control. Follow your diet, medication, and exercise routines very closely if you are being treated for hypertension.

Hypertension often has no symptoms, so you may not even feel that you have high blood pressure. Continue using this medicine as directed, even if you feel well. You may need to use blood pressure medication for the rest of your life.

Store metoprolol/Lopressor at room temperature away from moisture and heat.

Lopressor/Metoprolol SIDE EFFECTS

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have any of these serious side effects:

• feeling light-headed, fainting;
• cold feeling in your hands and feet.
• slow or uneven heartbeats;
• swelling of your ankles or feet;
• nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
• depression; or
• feeling short of breath, even with mild exertion;

Other less serious side effects are more likely to occur, such as:

• sleep problems (insomnia);
• decreased sex drive, impotence, or difficulty having an orgasm;
• anxiety, nervousness.
• vomiting;
• tired feeling; or

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What is the shelf life of the pills?

• The expiry date is mentioned on each blister. It is different for different batches. The shelf life is 2 years from the date of manufacture and would differ from batch to batch depending on when they were manufactured.