WHAT IS Avandaryl/Rosiglitazone maleate - glimepiride TABLETS?

GLIMEPIRIDE/Amaryl; ROSIGLITAZONE/Avandaryl helps to treat type 2 diabetes. It helps to control blood sugar. Treatment is combined with diet and exercise. This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

WHERE SHOULD I KEEP Avandaryl/Rosiglitazone maleate - glimepiride?

Keep out of the reach of children.

HOW SHOULD I USE Avandaryl/Rosiglitazone maleate - glimepiride?

Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Take this medicine with food. Take your doses at regular intervals. Do not take your medicine more often than directed. Do not stop taking except on your doctor's advice.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

Note: This medicine is only for you. Do not share this medicine with others.

WHAT IF I MISS A DOSE?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

WHAT SHOULD I WATCH FOR WHILE USING Avandaryl/Rosiglitazone maleate - glimepiride?

Visit your doctor or health care professional for regular checks on your progress. Learn how to check your blood sugar. Tell your doctor or health care professional if your blood sugar is high, you might need to change the dose of your medicine. If you are sick or exercising more than usual, you might need to change the dose of your medicine. Do not skip meals. Ask your doctor or health care professional if you should avoid alcohol. If you have symptoms of low blood sugar, eat or drink something containing sugar at once and contact your doctor or health care professional. Make sure family members know that you can choke if you eat or drink when you develop serious symptoms of low blood sugar, like seizures or unconsciousness. They must get medical help at once.

Wear a medical identification bracelet or chain to say you have diabetes, and carry a card that lists all your medications.

This medicine can make you more sensitive to the sun. Keep out of the sun. If you cannot avoid being in the sun, wear protective clothing and use sunscreen. Do not use sun lamps or tanning beds/booths.

WHAT MAY INTERACT WITH Avandaryl/Rosiglitazone maleate - glimepiride?

• thyroid hormones
• bosentan
• steroid medicines like prednisone/Sterapred or cortisone
• glyburide
• phenytoin/Dilantin er
• aspirin and aspirin-like medicines
• NSAIDs, medicines for pain and inflammation, like ibuprofen/Motrin or naproxen/Aleve
• medications for weight loss
• female hormones, like estrogens and birth control pills
• gemfibrozil/Lopid
• diuretics
• miconazole
• medicines for cold or congestion
• insulin
• phenothiazines like chlorpromazine/Thorazine, mesoridazine, prochlorperazine/Compazine, thioridazine/Mellaril
• rifampin
• medicines for high blood pressure like metoprolol/Toprol, propanolol
• MAOIs like Carbex, Eldepryl , Marplan, Nardil, and Parnate
• isoniazid
• methotrexate/Rheumatrex
• chloramphenicol/Chloromycetin

This list may not describe all possible interactions. Give your health care providers a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

WHAT SIDE EFFECTS MAY I NOTICE FROM Avandaryl/Rosiglitazone maleate - glimepiride?

Side effects that you should report to your doctor or health care professional as soon as possible:

• yellowing of the eyes or skin
• muscle aches, pains
• breathing problems
• feeling faint or lightheaded, falls
• swelling of the hands, legs, or feet
• changes in vision
• stomach pain
• low blood sugar (ask your doctor or healthcare professional for a list of these symptoms)
• allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
• fever, chills, sore throat
• dark urine
• high blood pressure
• unusually weak or tired

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

• nausea
• loss of appetite
• weight gain
• diarrhea
• headache

This list may not describe all possible side effects.

WHAT SHOULD I TELL MY HEALTH CARE PROVIDERS BEFORE I TAKE Avandaryl/Rosiglitazone maleate - glimepiride?

They need to know if you have any of these conditions:

• liver disease
• an unusual or allergic reaction to glimepiride/Amaryl, rosiglitazone/Avandaryl , other medicines, foods, dyes, or preservatives
• pregnant or trying to get pregnant
• severe infection or injury
• swelling of the arms, legs, or feet
• kidney disease
• heart disease
• diabetic ketoacidosis
• breast-feeding
• thyroid disease

What is the shelf life of the pills?

• The expiry date is mentioned on each blister. It is different for different batches. The shelf life is 2 years from the date of manufacture and would differ from batch to batch depending on when they were manufactured.