Provera/Medroxyprogesterone usp IS USED FOR:

Treating certain menstrual problems or uterine problems (eg, abnormal bleeding, endometrial hyperplasia). It may also be used for treating certain conditions as determined by your doctor.

Medroxyprogesterone/Provera is a progestin hormone. It works by altering the lining of the uterus.

BEFORE USING Provera/Medroxyprogesterone usp :

Tell your health care provider if you have any medical conditions, especially if any of the following apply to you:

• if you have allergies to medicines, foods, or other substances
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have diabetes, seizures (eg, epilepsy), migraines, asthma, heart problems, kidney problems, or a history of depression.
• if you are planning to become pregnant or are breast-feeding

Some MEDICINES MAY INTERACT with Medroxyprogesterone/Provera . Tell your health care provider if you are taking any of the following medicines.

• Rifampin because effectiveness of Medroxyprogesterone/Provera may be decreased.

This may not be a complete list of all interactions that may occur. Ask your health care provider if Medroxyprogesterone/Provera may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

HOW TO USE Provera/Medroxyprogesterone usp :

Use Medroxyprogesterone/Provera as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Medroxyprogesterone/Provera comes with an additional patient leaflet. Read it carefully and reread it each time you get Medroxyprogesterone/Provera refilled.
• Medroxyprogesterone/Provera may be taken with or without food.
• Take Medroxyprogesterone/Provera at the same time every day, with doses not more than 24 hours apart.
• If you miss a dose of Medroxyprogesterone/Provera , take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Medroxyprogesterone/Provera .

DO NOT USE Provera/Medroxyprogesterone usp IF:

• you are pregnant or may be pregnant.
• you are allergic to any ingredient in Medroxyprogesterone/Provera
• you have vaginal bleeding of unknown cause, or if you have a history of blood clots, bleeding in the brain (eg, stroke), liver problems, or breast or genital cancer.

Contact your doctor or health care provider right away if any of these apply to you.

POSSIBLE SIDE EFFECTS OF Provera/Medroxyprogesterone usp :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Acne; changes in menstrual flow, including breakthrough bleeding, spotting, or missed periods; dizziness; drowsiness; fever; headache; hot flashes; nausea; nervousness; pain; rash; sleeplessness; stomach pain; weakness; weight gain or loss.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); chest pain; depression; lumps in the breast or under the armpits; partial or complete loss of vision or changes in vision; shortness of breath; slurred speech; sudden loss of coordination; sudden or severe headache; swelling of fingers or ankles; tenderness, pain, or swelling of the calf; weakness, numbness, or pain in the arms or legs; yellowing of the skin or eyes.

IMPORTANT SAFETY INFORMATION:

• Medroxyprogesterone/Provera may cause dark skin patches on your face. Exposure to the sun may make these patches darker. If patches develop, use a sunscreen or protective clothing when exposed to the sun, sunlamps, or tanning booths.
• Medroxyprogesterone/Provera may cause drowsiness or dizziness. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Medroxyprogesterone/Provera . Using Medroxyprogesterone/Provera alone, with certain other medicines, or with alcohol may lessen your ability to drive or to perform other potentially dangerous tasks.
• Diabetes patients - Medroxyprogesterone/Provera may affect your blood sugar. Check blood sugar levels closely and ask your doctor before adjusting the dose of your diabetes medicine.
• PREGNANCY and BREAST-FEEDING: Do not use Medroxyprogesterone/Provera if you are pregnant. If you suspect that you could be pregnant, contact your doctor immediately. Medroxyprogesterone/Provera is excreted in breast milk. If you are or will be breast-feeding while you are using Medroxyprogesterone/Provera , check with your doctor or pharmacist to discuss the risks to your baby.
• Medroxyprogesterone/Provera is not recommended for use in CHILDREN; safety and effectiveness have not been confirmed.

What is the shelf life of the pills?

• The expiry date is mentioned on each blister. It is different for different batches. The shelf life is 2 years from the date of manufacture and would differ from batch to batch depending on when they were manufactured.