Wellbutrin/Wellbutrin sr Sustained-Release Tablets is used for:

Treating depression. It may also be used for other conditions as determined by your doctor.

Wellbutrin/Wellbutrin sr Sustained-Release Tablets is an antidepressant. It works in the brain to treat depression. Exactly how it works is not known.

How to use Wellbutrin/Wellbutrin sr Sustained-Release Tablets:

Use Wellbutrin/Wellbutrin sr Sustained-Release Tablets as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Wellbutrin/Wellbutrin sr Sustained-Release Tablets comes with an extra patient information sheet called a Medication Guide. Read it carefully. Read it again each time you get Wellbutrin/Wellbutrin sr Sustained-Release Tablets refilled.
• Take Wellbutrin/Wellbutrin sr Sustained-Release Tablets by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation.
• Swallow Wellbutrin/Wellbutrin sr Sustained-Release Tablets whole. Do not break, crush, or chew before swallowing.
• Several weeks may pass before your symptoms improve. Do not stop taking Wellbutrin/Wellbutrin sr Sustained-Release Tablets without checking with your doctor.
• Take your doses at the same times each day at least 8 hours apart unless directed otherwise by your doctor. This may help to decrease the risk of seizures with Wellbutrin/Wellbutrin sr Sustained-Release Tablets.
• Continue to take Wellbutrin/Wellbutrin sr Sustained-Release Tablets even if you feel well. Do not miss any doses.
• If you miss a dose of Wellbutrin/Wellbutrin sr Sustained-Release Tablets, skip the missed dose. Go back to your regular dosing schedule. Do not take more than 1 dose within 8 hours. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Wellbutrin/Wellbutrin sr Sustained-Release Tablets.

Before using Wellbutrin/Wellbutrin sr Sustained-Release Tablets:

Some medical conditions may interact with Wellbutrin/Wellbutrin sr Sustained-Release Tablets. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you or a family member has a history of bipolar disorder (manic depression), other mental or mood problems (eg, depression), suicidal thoughts or attempts, or alcohol or substance abuse
• if you have diabetes, kidney problems, high blood pressure, heart problems (eg, congestive heart failure), or a recent heart attack
• if you have a history of seizure, head injury, tumor in the brain or spinal cord, or liver problems (eg, cirrhosis)

Some MEDICINES MAY INTERACT with Wellbutrin/Wellbutrin sr Sustained-Release Tablets. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Amantadine/Symmetrel, antipsychotics (eg, haloperidol, risperidone/Risperdal), corticosteroids (eg, prednisone/Deltasone), insulin, levodopa, MAOIs (eg, phenelzine), nicotine patches, oral hypoglycemics (eg, glipizide/Glucotrol xl), other antidepressants (eg, fluoxetine/Rapiflux, amitriptyline/Elavil), sympathomimetics (eg, pseudoephedrine), theophylline/T-phyl tr, or tiagabine because they may increase the risk of Wellbutrin/Wellbutrin sr Sustained-Release Tablets's side effects
• Carbamazepine/Carbatrol, phenobarbital, or phenytoin/Dilantin because they may decrease Wellbutrin/Wellbutrin sr Sustained-Release Tablets's effectiveness
• Antiarrhythmics (eg, propafenone, flecainide), beta-blockers (eg, metoprolol/Lopressor), phenothiazines (eg, thioridazine/Mellaril), selective serotonin reuptake inhibitor (SSRI) antidepressants (eg, fluoxetine/Rapiflux), or tricyclic antidepressants (eg, nortriptyline/Aventyl) because the risk of their side effects may be increased by Wellbutrin/Wellbutrin sr Sustained-Release Tablets

This may not be a complete list of all interactions that may occur. Ask your health care provider if Wellbutrin/Wellbutrin sr Sustained-Release Tablets may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

Do NOT use Wellbutrin/Wellbutrin sr Sustained-Release Tablets if:

• you are allergic to any ingredient in Wellbutrin/Wellbutrin sr Sustained-Release Tablets
• you are taking any other medicine that contains bupropion/Wellbutrin sr
• you have a history of an eating disorder (eg, anorexia, bulimia) or seizures (eg, epilepsy)
• you are suddenly stopping the use of alcohol or sedatives (eg, benzodiazepines) after long-term use
• you are taking or have taken a monoamine oxidase inhibitor (MAOI) (eg, phenelzine) within the last 14 days

Contact your doctor or health care provider right away if any of these apply to you.

Important safety information:

• Wellbutrin/Wellbutrin sr Sustained-Release Tablets may cause drowsiness, dizziness, or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use Wellbutrin/Wellbutrin sr Sustained-Release Tablets with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
• Check with your doctor before you drink alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are taking Wellbutrin/Wellbutrin sr Sustained-Release Tablets; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.
• Wellbutrin/Wellbutrin sr Sustained-Release Tablets may increase your risk of seizures. Your risk may be greater if you also have certain medical conditions, use certain medicines, or if you drink large amounts of alcohol. Talk to your doctor to see if you may have a greater risk of seizures while taking Wellbutrin/Wellbutrin sr Sustained-Release Tablets.
• If you already drink alcohol or use sedatives, do not suddenly stop them without first checking with your doctor. Suddenly stopping them may increase your seizure risk.
• Do not take decongestants (eg, pseudoephedrine), stimulants, or diet pills while you are taking Wellbutrin/Wellbutrin sr Sustained-Release Tablets without first checking with your doctor. They may increase your risk of seizures.
• The risk of seizures may be greater if you take Wellbutrin/Wellbutrin sr Sustained-Release Tablets in high doses or for a long time. Do NOT take more than the recommended dose, change your dose, or use Wellbutrin/Wellbutrin sr Sustained-Release Tablets for longer than prescribed without checking with your doctor.
• Children, teenagers, and young adults who take Wellbutrin/Wellbutrin sr Sustained-Release Tablets may be at increased risk for suicidal thoughts or actions. Watch all patients who take Wellbutrin/Wellbutrin sr Sustained-Release Tablets closely. Contact the doctor at once if new, worsened, or sudden symptoms such as depressed mood; anxious, restless, or irritable behavior; panic attacks; or any unusual change in mood or behavior occur. Contact the doctor right away if any signs of suicidal thoughts or actions occur.
• If you have trouble sleeping, you may be taking your dose too close to bedtime. Talk with your doctor about changing your dosing schedule.
• Wellbutrin/Wellbutrin sr Sustained-Release Tablets contains the same ingredients as Zyban, a medicine used to help stop smoking. Do not take Wellbutrin/Wellbutrin sr Sustained-Release Tablets if you are also taking Zyban. Discuss any questions or concerns with your doctor.
• Use Wellbutrin/Wellbutrin sr Sustained-Release Tablets with caution in the ELDERLY; they may be more sensitive to its effects.
• Wellbutrin/Wellbutrin sr Sustained-Release Tablets should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.
• PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Wellbutrin/Wellbutrin sr Sustained-Release Tablets while you are pregnant. Wellbutrin/Wellbutrin sr Sustained-Release Tablets is found in breast milk. Do not breast-feed while taking Wellbutrin/Wellbutrin sr Sustained-Release Tablets.

Possible side effects of Wellbutrin/Wellbutrin sr Sustained-Release Tablets:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; dizziness; drowsiness; dry mouth; flushing; headache; increased sweating; increased urination; loss of appetite; nausea; nervousness; restlessness; ringing in the ears; stomach pain; taste changes; trouble sleeping; vomiting; weakness; weight changes.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); chest pain; confusion; delusions; fainting; fast or irregular heartbeat; fever, chills, or sore throat; hallucinations; hearing problems; menstrual changes; new or worsening mental or mood changes (eg, concentration problems, panic attacks, aggressiveness, agitation, anxiety, impulsiveness, irritability, hostility, exaggerated feeling of well-being or inability to sit still); red, swollen, blistered, or peeling skin; seizures; severe headache or dizziness; severe or persistent joint or muscle pain; severe or persistent nervousness, restlessness, or trouble sleeping; shortness of breath; suicidal thoughts or attempts; tremor; unusual swelling; vision changes; worsening depression.

What is the shelf life of the pills?

• The expiry date is mentioned on each blister. It is different for different batches. The shelf life is 2 years from the date of manufacture and would differ from batch to batch depending on when they were manufactured.